The majority of these operations were performed in the last two d

The majority of these operations were performed in the last two decades. Early mortality within 30 days of operation was 7.9% for repair and 17.6% for replacement (P = 0.29). The 1-, 5-, 10- and 25-year survival rates were 83.8, 74.5, 63.6 and Citarinostat 32.8% for tricuspid repair and 81.8, 68.2, 61.4 and 15.2% for tricuspid replacement, respectively. Preoperative loop diuretic dose (P = 0.0120) and preoperative haemoglobin level (P = 0.0377) were independent predictors of survival for all isolated tricuspid surgery, while preoperative creatinine level (P = 0.04) independently predicted

reoperation during the follow-up.

CONCLUSIONS: Both isolated tricuspid replacement and repair were associated with significant but acceptable early and late mortality with no statistically significant difference in cumulative survival. Preoperative

loop diuretic dose, haemoglobin and creatinine are individually associated www.selleckchem.com/products/ly3039478.html with survival and/or reoperation after isolated tricuspid valve surgery.”
“The purpose of this study is to review indications and results of surgical treatments of hepatocellular carcinoma (HCC). This tumor, which represents one of the most common malignancies worldwide, is characterized by its prominent development in patients with chronic liver disease (CLD). Liver transplantation (LT) is considered as the ideal treatment of limited HCC removing both tumor(s) and the pre-neoplasic underlying diseased liver. However, this treatment, which is not available in many countries, is restricted to patients with minimum risk of tumor recurrence under immunosuppression. The risk of recurrence is minimized in patients fulfilling the Milan criteria with a tendency to accept slight expansion of size in patients with favourable natural history and low AFP level. Increasing duration in the waiting list before LT leads several teams to use neoadjuvant therapies such as percutaneous ablation, TACE and liver resection. Liver resection Adavosertib ic50 in cirrhotic patients with good liver function remains the most available efficient treatment of patients with HCC. Better liver function assessment, understanding of the segmental liver anatomy

with more accurate imaging studies and surgical technique refinements are the most important factors that have contributed to reduce mortality with an expecting 5 years survival of 70%. There is considerable interest in combined treatment associating resection and LT. Transplantable patients with good liver function should be considered for liver resection as primary therapy and for LT in case of tumor recurrence. This salvage strategy is refined using pathological analysis of the resected specimen which identifies histological pejorative factors allowing selecting patients who should transplanted before recurrence.

The improvement of survival in HCC patients after surgical treatment results from refinements in surgical technique and better identification of adverse prognostic factors.

Fetal well-being measures included umbilical artery Dopplers, fet

Fetal well-being measures included umbilical artery Dopplers, fetal heart tracing and rate, and biophysical profile.

Measures were obtained at rest and immediately postexercise.

RESULTS: Groups were similar in age, body mass index, and gestational age. Maternal resting heart rate in the highly active group (61.6 +/- 7.2 beats per minute [bpm]) was significantly lower than the nonexercise (79.0 +/- 11.6 bpm) and regularly active (71.9 +/- 7.4 bpm) groups (P<.001). Treadmill time was longer in highly active (22.3 +/- 2.9 minutes) than regularly active (16.6 +/- 3.4) and nonexercise selleck (12.1 +/- 3.6) groups (P<.001), reflecting higher fitness. With moderate exercise, all umbilical artery Doppler indices were similar pre-exercise and postexercise among groups. With vigorous exercise, Dopplers were similar in regularly and highly active women with statistically significant decreases postexercise (P<.05). The group x time interaction was not significant. Postexercise fetal heart tracings met criteria for reactivity within 20 minutes

after all tests. Biophysical profile scores were reassuring.

CONCLUSION: GNS-1480 mw This study supports existing guidelines indicating pregnant women may begin or maintain an exercise program at moderate (inactive) or vigorous (active) intensities. (Obstet Gynecol 2012;119:603-10) DOI: 10.1097/AOG.0b013e31824760b5″
“The enzymes and pathways of steroidogenesis are central to an understanding of adrenarche. The quantitative regulation of steroidogenesis occurs Sapitinib concentration at the first step, the conversion of cholesterol to pregnenolone. Chronic quantitative regulation

is principally at the level of transcription of the CYP11A1 gene encoding P450scc, which is the enzymatically rate-limiting step. Acute regulation is mediated by the steroidogenic acute regulatory protein (StAR), which facilitates the rapid influx of cholesterol into mitochondria, where P450scc resides. Qualitative regulation, which determines the type of steroid produced in a cell, is principally at the level of P450c17 (CYP17). In the absence of P450c17 in the zona glomerulosa, C21 deoxy steroids are produced, leading to the mineralocorticoid, aldosterone. In the presence of the 17 alpha-hydroxylase but not the 17,20 lyase activity of P450c17 in the zona fasciculata, C21, 17-hydroxy steroids are produced, leading to the glucocorticoid, cortisol. When both the 17 alpha-hydroxylase and 17,20 lyase activities of P450c17 are present in the zona reticularis, the androgen precursor DHEA is produced. The discrimination between 17 alpha-hydroxylase and 17,20 lyase activities is regulated by two post-translational events, the serine phosphorylation of P450c17 and the allosteric action of cytochrome b(5), both of which act to optimize the interaction of P450c17 with its obligatory electron donor, P450 oxidoreductase.


“Background: Human coronavirus NL63 (HCoV-NL63) has recent


“Background: Human coronavirus NL63 (HCoV-NL63) has recently been implicated as a common cause of croup in children. Selleckchem BEZ235 This study was performed to evaluate viruses associated with croup in children, with an emphasis on HCoV-NL63.

Methods: Nasopharyngeal aspirates were prospectively collected from 182 children hospitalized with croup at Seoul National University Bundang Hospital from January 2005 to June 2009. Multiplex reverse-transcriptase polymerase chain reaction was conducted for detection of 11 respiratory viruses, and medical records were reviewed.

Results: Viruses were identified in 147 (80.8%) of the 182 croup patients. The 3 most commonly detected viruses were parainfluenza virus type 1 (PIV1)

in 44 (24.2%) patients, HCoV-NL63 in 30 (16.5%) patients, and influenza A virus in 25 (13.7%) patients. Other detected viruses were rhinovirus PF-03084014 solubility dmso in 22 (12.1%) patients, PIV type 3 and respiratory syncytial virus in 15 (8.2%) patients, human bocavirus in 8 (4.4%) patients, and several others in a few patients. Coinfections with >2 viruses were found in 20 (11%) patients. HCoV-NL63 was identified primarily in winter, which coincides with the peak occurrence of croup. Patients with HCoV-NL63 infection were younger than those who were positive for PIV1 (median age 13 months versus 21 months, P = 0.006) and had shorter fever duration than influenza A virus infection (median

1.5 days versus 4 days, P = 0.000).

Conclusions: PIV1 and HCoV-NL63 were most commonly associated with patients who were hospitalized with croup. HCoV-NL63 is prevalent in winter and is associated with younger age and with shorter fever duration.”
“Introduction and hypothesis This study was conducted to assess national rates in stress urinary incontinence (SUI) surgery in the USA from 1998 to 2007. Methods We utilized the 1998-2007 Nationwide Inpatient Sample and assessed women aged 20 years and older who underwent selleck SUI surgery based on the International

Classification of Diseases, 9th Revision (ICD-9) procedure and diagnosis codes.

Results The total number of SUI surgeries performed during this 10-year period was 759,821. The annual number of procedures increased from 37,953 in 1998 to 94,910 in 2007. The type of SUI surgery performed also changed (p<0.001). In 1998, retropubic suspensions represented 52.3%, decreasing to 13.8% in 2007. “”Other repair of SUI”" (ICD-9 59.79) comprised 22.4% in 1998, increasing to 75.2% in 2007, likely representing midurethral slings.

Conclusions The total number and incidence rates of SUI surgeries have increased from 1998 to 2007. The type of SUI surgery performed has also changed significantly, likely secondary to adoption of midurethral slings.”
“Introduction: Unrestricted somatic stem cells (USSC) derived from umbilical cord blood are an attractive alternative to human embryonic stem cells (hESC) for cellular therapy.

6% of intracellular substances (calculated by the proportion of t

6% of intracellular substances (calculated by the proportion of the intracellular nucleotide release) is sufficient to lead to cell death. The use of media with different ionic strength levels to create osmotic shock showed that the treatment of E. coli cells with cold plasma significantly decreased the cell wall strength.”
“Individuals with a family history of alcoholism (FH+) are at enhanced risk of developing an alcohol or other substance use disorder relative to those Without this history (FH-). Recent studies comparing FH+ and FH- individuals

have revealed differences in cognition, emotion processing, sociability, and decision-making. These differences GSI-IX manufacturer suggest possible altered brain functioning in FH+ individuals that may play a crucial role in Vulnerability to substance use disorders. In the present study, 15 FH+ and 19 FH- individuals performed the Iowa GamblingTask (IGT), a simulated card game requiring integration of payoff-to-penalty ratios, while undergoing functional magnetic resonance imaging. All participants performed the task more conservatively as the session progressed, and the FH groups see more achieved similar payoffs by the end of the game. Imaging revealed a distributed network of brain regions

that was engaged when subjects performed this task, including the right inferior frontal and postcentral gyri, left parahippocampal gyros, insula and selleck inhibitor precuneous cortices, left inferior and superior parietal lobules, left lentiform nucleus and bilateral culmen, claustrum,

lingual gyri and cerebellar tonsils. Despite a lack of behavioral differences between groups, the FH+ participants showed significantly more activation in the left dorsal anterior cingulate cortex and left caudate nucleus. These findings correspond to models of risk in FH+ persons that postulate biases in brain decision-making systems as underlying elevated risk for alcoholism. (C) 2008 Elsevier Ireland Ltd. All rights reserved.”
“The influence of the concentration and time of addition of cosubstrate (pentanol) on the molecular weight (MW) of the polyhydroxybutyrate/ valerate (PHBV) copolymer synthesized by Methylobacterium extorquens G-10 during cultivation in a methanol-containing medium has been studied. It was shown that an increase in the pentanol concentration to 20% in a mixture with methanol stimulated the biosynthesis of PHBV with a MW of similar to 1500 kDa and increased the content of valerate up to 50%, especially when pentanol was added to the log phase culture. High pentanol concentrations are toxic for the producer and reduce the total yield of PHBV. An MW increase to 1500 kDa lowers the melting temperature (from 172 to 162 degrees C) and the crystallinity degree (from 63 to 8%) of the biopolymer but increases its elasticity. The revealed variability of PHBV properties extends considerably the potential application areas of synthetic bioplastics.

968, p<0 001), and between free urinary cortisol and urinary 1

968, p<0.001), and between free urinary cortisol and urinary 17-OHCS (R = 0.733, p = 0.025). The salivary and urinary hormones studied were independent of body mass index. This study shows the relevance of salivary cortisol and melatonin, although lower than in plasma, in testing adrenal and pineal function as markers of circadian rhythms. The data are of interest for the diagnosis and treatment of chronobiological disorders in prepubertal children.”
“Postherpetic neuralgia has been variably

GSK923295 defined but is generally understood to be pain that persists for longer than a few months after an attack of herpes zoster. Pain persists for years in approximately 10 % of those afflicted with HTS assay acute herpes zoster. The likelihood of postherpetic neuralgia increases with older age, severity of the zoster, trigeminal location, and other factors. Postherpetic neuralgia is a neuropathic pain and treatment usually involves sequential trials of topical and systemic drugs; a variety of other therapies may be considered in refractory cases. A new topical capsaicin 8 % patch has been approved for this indication based on the positive studies in patients with non-trigeminal

postherpetic neuralgia. Experience with the use of the capsaicin 8 % patch for trigeminal distribution neuralgia is lacking. We report a case of trigeminal postherpetic neuralgia which was safely and effectively treated with capsaicin 8 % patch.”
“Background: High-density lipoproteins (HDLs) influence the generation of prostacyclin via cyclooxygenase stimulation. Prostaglandins represent an important compensatory pathway CX-6258 in vivo in advanced heart failure (HF). Whether HDL levels discriminate prognosis in HF remains unknown.

Methods: We prospectively evaluated the prognostic relationship of HDL levels in severe HF by

examining 132 consecutive patients listed for heart transplantation (52 +/- 11 years of age, 80% men, 79% white, mean follow-up 18 months). Using population mean HDL levels (HDL <33 mg/dl [n = 47] vs >= 33 mg/dl [n = 85]), patients were grouped and followed for the primary composite end-points of HF hospitalizations or death, stratified by underlying etiology (non-ischemic, n = 52; ischemic, n = 80).

Results: Patients with HDL <33 mg/dl had lower serum sodium (135 vs 137 mEq/liter, p = 0.008), higher total bilirubin (1.3 vs 0.7 mg/dl, p < 0.001) and higher uric acid (7.6 vs; 6.7 mg/dL, p = 0.048) levels, but similar serum creatinine compared with the >= 33 mg/dl HDL group. Survival analysis, using a Cox proportional hazards model, revealed reduced HDL (<33 mg/dl) as the most significant independent predictor of HF hospitalizations or death, independent of underlying etiology. Low-cholesterol and low-density lipoprotein (LDL)-cholesterol alone were not found to be independently predictive Of Outcome.

Injection site pain was measured using a visual analogue scale at

Injection site pain was measured using a visual analogue scale at injection (time 0) and 15, 30, 45, and 60 minutes after injection. Patients were asked to return for an evaluation after 2 weeks and to complete a self-assessment questionnaire during the follow-up visit.

RESULTS

There was more than 50% less pain associated with the dermal gel with lidocaine than

with the same filler without check details lidocaine at all time points (p <.05). The greatest difference in pain was recorded at the time of injection, and then the effect gradually declined over the 60-minute period. Both fillers were well tolerated, and there was no difference in outcome after 2 weeks.

CONCLUSION

Addition of lidocaine to a filler resulted in significantly

less pain associated with the procedure without compromising outcomes.

Gary Monheit, MD, is a Consultant and Clinical Investigator to Genzyme. Nathan Bachtell, MD, Denise Eng, BS, and Lena Holmdahl, MD, PhD, are employees of Genzyme Corporation.”
“Contrary to traditional belief, breast milk is not a sterile fluid, even in healthy women. Breast milk may contain pathogenic bacteria that could cause serious infections especially in premature infants. There is no recommendation to evaluate breast milk routinely for pathogenic bacteria. However discontinuation of breastfeeding is not recommended even the mother had mastitis, because it is believed this will not pose a risk to infant. This selleck inhibitor is the

report of a premature infant born at the 32nd Selleckchem JQ1 gestational week who was readmitted to neonatal intensive care unit with late-onset Staphylococcus aureus sepsis. While searching for the transmission route of the infection, the breast milk was assessed. Although the mother did not have any symptoms of breast inflammation, S. aureus isolates, genetically 99% similar to those from the infant blood samples, were documented in the breast milk.

Conclusion: Breast milk may contain pathogenic bacteria, even when expressed, stored and transported properly. When evaluating the source of a S. aureus infection in preterm infants, breast milk might be the source of the infection, even if the mother has no sign of mastitis.”
“In the last years, the decontamination and disinfection of waters by means of direct or integrated electrochemical processes are being considered as a very appealing alternative due to the significant improvement of the electrode materials and the coupling with low-cost renewable energy sources. Many electrochemical technologies are currently available for the remediation of waters contaminated by refractory organic pollutants such as pharmaceutical micropollutants, whose presence in the environment has become a matter of major concern.

Conclusion Gelam honey-induced differential expression of MAPK,

Conclusion. Gelam honey-induced differential expression of MAPK, NF-kappa B, IRS-1 (ser307), and Akt in HIT-T15 cells shows that Gelam honey exerts protective effects against diabetes-and hyperglycemia-induced oxidative stress by improving insulin content and insulin resistance.”
“Objectives: Human papillomavirus (HPV) infection is a major risk factor for cervical disease. Using baseline data from the HIV-infected cohort of Evandro Chagas Clinical Research Institute at Fiocruz, Rio de Janeiro, Brazil, factors associated with an increased prevalence of HPV were

assessed.

Methods: Samples from 634 HIV-infected women were tested for the presence of HPV infection using hybrid capture 11 and polymerase chain reaction. Prevalence ratios (PR) were estimated using Poisson regression analysis with robust variance.

Results: The

overall MDV3100 chemical structure prevalence of HPV infection was 48%, of which 94% were infected with a high-risk HPV. In multivariate analysis, factors independently associated with infection with high-risk HPV type were: younger age (<30 years of age; PR 1.5, 95% confidence interval (CI) 1.1-2.1), current or prior drug use (PR 1.3, 95% CI 1.0-1.6), self-reported history of HPV infection (PR 1.2, 95% CI 0.96-1.6), condom use in the last sexual intercourse (PR 1.3, see more 95% CI 1.1-1.7), and nadir CD4+ T-cell MK-2206 order count <100 cells/mm(3) (PR 1.6, 95% CI 1.2-2.1).

Conclusions: The estimated prevalence of high-risk HPV-infection among HIV-infected women from Rio de Janeiro, Brazil, was high. Close monitoring of HPV-related effects is warranted in all HIV-infected women, in particular those of younger age and advanced immunosuppression. (C) 2008 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.”
“Oral antidiabetic drugs (OADs) are used for more than a half-century in the treatment of type 2 diabetes. Only in the last five years, intensive research has been conducted in the pharmacogenetics of these drugs based mainly on the retrospective register studies, but only a handful

of associations detected in these studies were replicated. The gene variants in CYP2C9, ABCC8/KCNJ11, and TCF7L2 were associated with the effect of sulfonylureas. CYP2C9 encodes sulfonylurea metabolizing cytochrome P450 isoenzyme 2C9, ABCC8 and KCNJ11 genes encode proteins constituting ATP-sensitive K+ channel which is a therapeutic target for sulfonylureas, and TCF7L2 is a gene with the strongest association with type 2 diabetes. SLC22A1, SLC47A1, and ATM gene variants were repeatedly associated with the response to metformin. SLC22A1 and SLC47A1 encode metformin transporters OCT1 and MATE1, respectively. The function of a gene variant near ATM gene identified by a genome-wide association study is not elucidated so far.

) C A Meyer and roots of Diplomorpha ganpi (Sieb et Zucc ) Nak

) C. A. Meyer and roots of Diplomorpha ganpi (Sieb. et Zucc.) Nakai, respectively. Nine known compounds including diarylpentanoids (3-6), phenylpropanoid derivatives (7-9), (+)-afzelechin (10) and apiosylskimmin (11) were also isolated for the first time from D. ganpi. Structures of these compounds were elucidated on the basis of spectroscopic

data. (C) 2012 Phytochemical Society of Europe. Published by Elsevier B. V. All rights reserved.”
“OBJECTIVE: The purpose of this case-control study was to evaluate risk factors associated with death in children with severe dengue.

METHODS: The clinical condition of hospitalized patients with severe dengue who died (cases, n = 18) was compared with that of hospitalized patients with severe Staurosporine dengue who survived (controls, n = 77). The inclusion criteria for Temsirolimus this study were age under 13 years; hospital admission in Sao

Luis, northeastern Brazil; and laboratory-confirmed diagnosis of dengue.

RESULTS: Severe bleeding (hemoptysis), a defining criterion for dengue severity, was the factor most strongly associated with death in our study. We also found that epistaxis and persistent vomiting, both included as warning signs in the World Health Organization (WHO) classification of dengue, were strongly associated with death. No significant association was observed between any of the laboratory findings and death.

CONCLUSIONS: The finding that epistaxis and persistent vomiting were also associated with death in children with severe dengue was unexpected and deserves to be explored in future studies. Because intensive care units are often limited in resource-poor settings, any information that can help to distinguish patients with severe

dengue with a higher risk to progress to death may be crucial.”
“Ocular emergencies such as retinal detachments, mechanical globe injuries, and chemical injuries can cause permanent vision loss if they are not recognized and treated promptly. Family physicians should be familiar with the signs and symptoms associated with each condition, and be able to perform a basic eye examination to assess the situation. The assessment includes measurement of visual acuity, pupillary examination, visual field testing, slit lamp or penlight examination of the anterior segment of the eye, and VEGFR inhibitor direct funduscopic examination. Patients with symptomatic floaters and flashing lights require a dilated fundoscopic examination and prompt referral to an ophthalmologist for evaluation of a retinal tear or detachment. A globe laceration or rupture should be suspected in patients with a recent history of trauma from a blunt or penetrating object. Prophylactic oral antibiotics can be administered after a globe injury to prevent endophthalmitis, and the eye should be covered with a metal shield until evaluation by an ophthalmologist.

Summary

Future research should move beyond cross-secti

Summary

Future research should move beyond cross-sectional studies and include longitudinal assessment of QOL. In addition, given the success with extending the lives of young patients with cardiac conditions, it is important that strategies

focused on patient and family QOL are also advanced.”
“Bioactive compounds such as phenolics and essential oils involved in medicinal plants are beneficial for human health. Medicinal plants are potential sources of natural antioxidants. The genus of Achillea is comprised of more than 100 species worldwide with different medicinal applications. Nineteen species of Achillea have been recognized in Iran. Since the endemic medicinal species are considered Vorinostat as new natural sources of bioactive compounds, in this study, total phenolics and antioxidant activity of three endemic Achillea species (A. pachycephalla, A. aucherii and A. kellalensis) were compared with a synthetic antioxidant butylated hydroxytoluene (BHT). Total phenolic content was determined according to the Folin-Ciocalteu method and varied from 15.55 mg in A. aucherii to 60.65 mg tannic acid/1 g of dry product in A. pachycephalla.

Antioxidant activity of methanolic extract evaluated according to 1,1-diphenyl-2-picryl-hydrazyl (DPPH), ferric thiocyanate (FTC) and beta-carotene-linoleic acid Buparlisib ic50 assay. In DPPH assay, A. aucherii showed the highest IC50 (844 mu g/ml), while A. kellalensis and A. pachycephalla possessed Stem Cell Compound Library high throughput 518 mu g/ml and 248 mu g/ml, respectively. For reducing power, A. pachycephalia had the highest absorbance

in 700 nm (2.601), while A. aucherii possessed the lowest one (0.236). The results showed that three studied endemic species had acceptable antioxidant activity and can be introduced as important sources of natural antioxidants for pharmaceutical and medical purposes. (C) 2013 Elsevier B.V. All rights reserved.”
“Physical activity has been shown to increase following obesity surgery; however, changes in sedentary behavior in this setting are not known. Our aim was to describe changes in both physical activity and sedentary behavior of obese patients after gastric bypass (GBP) and their relationships with changes in body composition.

Physical activity, time spent watching TV as typical sedentary behavior (self-report), and body composition (DXA) were assessed before and 6 and 12 months after GBP in 86 obese patients (67 women, 24-66 years old, BMI 41.3-53.5 kg/m(2)).

One year after GBP (mean loss of weight -37.1 kg, fat mass -25.7 kg, lean body mass -9.4 kg), leisure-time physical activity (LTPA) significantly increased from 2.0 (SD 3.7) to 3.8 (5.4) h/week and from 7.2 (12.5) to 14.1 (20.1) MET-h/week (MET: metabolic equivalent task), the number of LTPA performed increased from 1.3 (1.3) to 1.8 (1.4), and TV time decreased from 3.0 (1.6) to 2.4 (1.4) h/day (all p < 0.05).

8 nm Raman analysis showed a strong peak at 136 cm(-1) Due to t

8 nm. Raman analysis showed a strong peak at 136 cm(-1). Due to the nanocrystalline nature, the threshold field (5.5 V/mu m) and approximate work function values were high, making the films a very efficient field emitter. (C) 2011 American Institute of Physics. [doi:10.1063/1.3585864]“
“The hypolipidemic NCT-501 supplier activity of Symplocos cochinchinensis S. Moore leaves was studied in Triton WR-1339- and high fat diet-induced hyperlipidemic

rats. In Triton WR-1339-induced hyperlipidemic rats, the hexane extract (250 and 500 mg/kg) exerted a significant (P < 0.01) lipid-lowering effect compared to ethyl acetate and methanol extracts, as assessed by the reversal of the plasma levels of total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C). In high check details fat diet-fed hyperlipidemic rats, the hexane extract (250 and 500 mg/kg) caused

the lowering of lipid levels in the plasma and liver. The hypolipidemic activity of S. cochinchinensis leaves was compared with fenofibrate, a known lipid-lowering drug, in both models.”
“Acoustic metamaterials with negative dynamic mass density have been shown to demonstrate a five-fold increase in transmission loss (TL) over mass law predictions for a narrowband (100 Hz) at low frequencies (100-1000 Hz). The present work focuses on the scale-up of this effect by examining the behavior of multiple elements arranged in arrays. Single membranes were stretched over rigid frame supports and masses were attached to the center of each divided cell. The TL behavior was measured for multiple configurations

with different magnitudes of mass distributed across each of the cell membranes in the array resulting in a multipeak click here TL profile. To better understand scale-up issues, the effect of the frame structure compliance was evaluated, and more compliant frames resulted in a reduction in the TL peak frequency bandwidth. In addition, displacement measurements of frames and membranes were performed using a laser vibrometer. Finally, the measured TL of the multi-celled structure was compared with the TL behavior predicted by finite element analysis to understand the role of nonuniform mass distribution and frame compliance. (C) 2011 American Institute of Physics. [doi:10.1063/1.3583656]“
“A novel sugar ester poacynose (1) was isolated from the flowers of Poacynum hendersonii together with 31 known compounds. The structure of 1 was established mainly on the basis of 1D and 2D NMR spectral data. Among the isolates, several constituents, such as kaempferol 3-O-sophoroside (5), picein (16), and 4-hydroxybenzoic acid 4-O-beta-d-glucopyranoside (17) moderately promoted adipogenesis of 3T3-L1 cells. In addition, simultaneous quantitative analysis of eight flavonoid constituents from the flower and leaf parts of P. hendersonii was developed.