Summary

Future research should move beyond cross-secti

Summary

Future research should move beyond cross-sectional studies and include longitudinal assessment of QOL. In addition, given the success with extending the lives of young patients with cardiac conditions, it is important that strategies

focused on patient and family QOL are also advanced.”
“Bioactive compounds such as phenolics and essential oils involved in medicinal plants are beneficial for human health. Medicinal plants are potential sources of natural antioxidants. The genus of Achillea is comprised of more than 100 species worldwide with different medicinal applications. Nineteen species of Achillea have been recognized in Iran. Since the endemic medicinal species are considered Bcl-2 inhibitor as new natural sources of bioactive compounds, in this study, total phenolics and antioxidant activity of three endemic Achillea species (A. pachycephalla, A. aucherii and A. kellalensis) were compared with a synthetic antioxidant butylated hydroxytoluene (BHT). Total phenolic content was determined according to the Folin-Ciocalteu method and varied from 15.55 mg in A. aucherii to 60.65 mg tannic acid/1 g of dry product in A. pachycephalla.

Antioxidant activity of methanolic extract evaluated according to 1,1-diphenyl-2-picryl-hydrazyl (DPPH), ferric thiocyanate (FTC) and beta-carotene-linoleic acid Erastin nmr assay. In DPPH assay, A. aucherii showed the highest IC50 (844 mu g/ml), while A. kellalensis and A. pachycephalla possessed Milciclib concentration 518 mu g/ml and 248 mu g/ml, respectively. For reducing power, A. pachycephalia had the highest absorbance

in 700 nm (2.601), while A. aucherii possessed the lowest one (0.236). The results showed that three studied endemic species had acceptable antioxidant activity and can be introduced as important sources of natural antioxidants for pharmaceutical and medical purposes. (C) 2013 Elsevier B.V. All rights reserved.”
“Physical activity has been shown to increase following obesity surgery; however, changes in sedentary behavior in this setting are not known. Our aim was to describe changes in both physical activity and sedentary behavior of obese patients after gastric bypass (GBP) and their relationships with changes in body composition.

Physical activity, time spent watching TV as typical sedentary behavior (self-report), and body composition (DXA) were assessed before and 6 and 12 months after GBP in 86 obese patients (67 women, 24-66 years old, BMI 41.3-53.5 kg/m(2)).

One year after GBP (mean loss of weight -37.1 kg, fat mass -25.7 kg, lean body mass -9.4 kg), leisure-time physical activity (LTPA) significantly increased from 2.0 (SD 3.7) to 3.8 (5.4) h/week and from 7.2 (12.5) to 14.1 (20.1) MET-h/week (MET: metabolic equivalent task), the number of LTPA performed increased from 1.3 (1.3) to 1.8 (1.4), and TV time decreased from 3.0 (1.6) to 2.4 (1.4) h/day (all p < 0.05).

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