51:1 (338:224), The three cause of lower gastrointestinal bleeding in male were inflammatory bowel disease, cancer, polyps; and in female were tumors, inflammatory bowel disease, perianal disease.The constitute ratio of male and female had no significant differences (P > 0.05). In this research, lower gastrointestinal hemorrhage deaths was 14 cases(562 cases total), the fatality rate was 2.5%.The older group was 10(older group patients was 241 cases), accounting for 4.1%; non-elderly group was 5(it’s patients was 341

cases), accounting Silmitasertib for 1.5%. There were a total of 135 cases (56%) coexisting diseases in the older group, and 21.2% in the non-elderly group respectively (P < 0.05). In this research, 362 cases have been diagnosed by colonoscopy, accounting for 64.4%.Comprehensive capsule endoscopy, Double-balloon enterscopy,

surgical instruments and means of imaging diagnosis rate was 92.3%. Conclusion: Tumors, inflammatory bowel disease, polyps were the three major causes of lower gastrointestinal hemorrhage. The age had significant differences (P < 0.05) in lower gastrointestinal hemorrhage rather than sex. Colonoscopy was the main means of diagnosis of lower gastrointestinal bleeding, comprehensive use of capsule endoscopy, colonoscopy, imaging tests and surgical means could improve the diagnosis rate of lower gastrointestinal bleeding. Key Word(s): 1. LGIH; 2. the causes; 3. mortalities; 4. inspection means; Presenting Author: XIJUN GUO Additional Authors: ZHONGXU FENG, YING SUN, SU YANG, YANQIU LIU, YOUJIA LV Corresponding Author: XIJUN GUO Affiliations: Center Hospital of Jilin City Objective: To PLX4032 evaluate clinical therapeutic effect of endoscopic sclerotherapy in treatment of acute upper gastrointestinal bleeding by Dieulafoy disease. Methods: Review and analyze clinical data of 11 patients with acute upper gastrointestinal bleeding by Dieulafoy disease after endoscopic sclerotherapy from January 1999 to December

MCE 2012. Results: 11 patients diagnosed by endoscopy for Dieulafoy disease bleeding (8 males, 3 females, age 41–69 years old), treated with endoscopic sclerotherapy, inject on 2–3 points 1–2 mm surrounding the bleeding parts. Sclerosing agent in each injection contains 5% Morrhuate Sodium (3 cases) or 1% Aethoxysklerol (3 cases) or Lauromacrogol (5 cases). All patients were to stop bleeding (the hemostatic success rate of 100 %). Conclusion: Endoscopic sclerotherapy is a safe and effective method in treatment of Dieulafoy disease bleeding. Key Word(s): 1. Dieulafoy disease; 2. Endoscopic; 3. Sclerosing agent; Presenting Author: WEIMIN MU Additional Authors: CHUANLEI LIU, SHUJUAN ZHOU Corresponding Author: WEIMIN MU Affiliations: Department of Gastroenteroloy, 222 Hospital of PLA,Number 340,Yushan Road Objective: To analysis the causes of upper gastrointestinal bleeding in patients with hepatic cirrhosis.